A study by the Agostino Gemelli University Polyclinic Foundation IRCCS in Rome sheds light on a little-known aspect: the persistence of Covid-19 symptoms after weeks of diagnosis and long after patients are discharged from hospital.
In the waning phase of the pandemic, starting from April 21, 2020, the Foundation has set up an outpatient service for people discharged from the hospital. The research results have been published on JAMA. Patients were asked to retrospectively report the presence or absence of symptoms during the acute phase of the disease and whether each symptom persisted at the time of the next visit in the clinic. People also had to evaluate theirs quality of life from 0 to 100 before COVID-19 and at the time of the visit. A difference of 10 points defined the deterioration of the quality of life.
Long tail of the disease
From 21 April to 29 May 2020 143 patients were evaluated. The average age was 56 for men and 53 for women. During hospitalization, 72.7% of participants had evidence of interstitial pneumonia. The average length of hospital stay was 13.5 days; 21 patients (15%) had been helped with non-invasive ventilation and 7 patients with invasive mechanical ventilation. Patients have been evaluated on average 60.3 days after onset the first symptom COVID-19; at the time of evaluation, only 18 subjects were completely free of any symptoms COVID-19 related, while 32% had 1 or 2 symptoms and 55% had 3 or more. None of the patients had fever or signs or symptoms of acute disease. Worsening quality of life was observed in 44.1% of patients. The study table (reported below, ed) shows that a high percentage of individuals still reported fatigue (53.1%), dyspnoea (43.4%), joint pain (27.3%) and chest pain (21.7%). 87.4% reported the persistence of at least 1 symptom, in particular fatigue and dyspnea.
The long-standing sick
a scientific study on a phenomenon little known and debated, but which in Italy has kept many people’s lives at home and upset. The long-term sick (we talked about it WHO), an unhappy condition that continues with ups and downs of often debilitating symptoms, but not serious enough to require hospitalization; individuals who have perhaps never made a tampon because “not sick enough”, who cannot resume their life and who often they are not believed by doctors and family members. Self-help groups have sprung up in the US that have estimated 3,700 members whose symptoms are lasted more than 30 days. For many, it is months and the symptoms resemble those of chronic fatigue syndrome (ME / CFS).
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