Coronavirus is hot, the expert: suffers but will not disappear. Vaccine? It risks being ineffective

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The Coronavirus suffers from the hot but it will not disappear». He says this to Adnkronos Salute Pasquale Mario Bacco, coroner and researcher of Meleam, company specializing in occupational medicine. For virologist Guido Silvestri, a professor at Emory University in Atlanta, the virus will return in December.

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With the increase in temperatures, the debate among experts on the effect of heat on the new coronavirus becomes increasingly heated. «Sars-CoV-2, like all coronaviruses, is significantly conditioned by the climate. In the laboratory we have seen that, by increasing the temperature of the culture media by a few degrees centigrade and then bringing it to the range of 25-30 degrees, about 53% of the strains do not survive and the remaining shows about 12 times lower activity ».

In short, according to Bacchus Sars-CoV-2 will suffer the heat. “In the summer, the virus is expected to exhibit very limited activity with very little aggression, but since it manages to survive, it will probably reappear as temperatures drop. In short, it will not go away entirely. My idea is that it will not disappear, as Sars did, “recalls the expert. Being “sensitive to the climate, Sars-CoV-2 will always manifest itself in a more incisive way in the colder areas of Italy,” adds the researcher.

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«The virus in our view – continues Bacchus – shows some sensitive mutations, also carried out in a short time. This makes us increasingly think that the possibility of making a vaccine that can be objectively effective for a time worthy of consideration is scarce. At the moment – he specifies – the observed mutations mainly concern genomic areas defined as introns, by definition poorly coding ». «Finally, we are finding, with increasing frequency, viral protein strands in biological liquids; at the moment this observation, although interesting, does not seem to have important repercussions on the evolution of the microorganism “, he concludes.

“We are now twenty-one days since the reopening of May 4, and even the shadow of the dreaded return of the virus”, underlines the virologist Guido Silvestri, professor at Emory University in Atlanta, taking stock of the Covid situation in Italy. «The retreat continues – Silvestri writes on Fb – We are on the 51st consecutive day when ICU admissions for Covid-19 in Italy drop, from 572 to 553, then 19 others, and we are now at 13.6% of the peak. The number of hospital admissions also drops, from 8,695 to 8,613, and active cases, from 57,752 to 56,595, therefore of other 1,157 units ».“We are on the 52nd consecutive day of drop in ICU admissions for Covid-19 in Italy, from 553 to 541, and we are now at 13.26% of the peak”. In addition, 22 days later “since the reopening of May 4, there are no signs of the virus flashing back”. And more in the world These are the two positive trends highlighted by virologist Guido Silvestri, professor at Emory University in Atlanta. In the usual space that he christened ‘Pills of optimism’ on his Facebook page, the expert takes stock of the situation of the Sars-Cov-2 coronavirus emergency. The most encouraging data come from the ICU counter, even if «as my colleagues in the field of intensivism point out – he underlines – it is possible that the final phase of this decline is slow if the residual stays are long. The number of total hospitalizations and active cases also fell (from 55,695 to 55,300, therefore of other 1,395 units) ». And even looking beyond national borders the situation appears encouraging for Silvestri, who attacks: “I have the vague feeling that the catastrophist’s job is becoming tiring”.

In Germany «there is a progressive attenuation of the health impact of Covid-19, with 298 cases (431 yesterday) and only 10 deaths. The famous declarations of certain subjects on the R0 “, the contagiousness index,” which had magically become higher than 1 the day after the reopening were, how to say, not exactly among the most sagacious. In France 35 deaths, one of the lowest counts for several weeks, while only 6 deaths are reported in Sweden. In the world yesterday the number of deaths / day is the lowest since March ». Positive signs also from two studies on vaccine candidates, one published in Lancet (phase I in humans of the Ad5-based vaccine by CanSino Biologicals) and the other in Science (pre-clinical study in the macaque of a DNA vaccine): « In both, vaccines induce the production of antibodies that neutralize the virus, and in Jingyou Yu’s study, “the one published in Science,” protect against disease. Optimism comes from science, “concludes Silvestri.

Last updated: 16:22 © RESERVED REPRODUCTION



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