Experiment at Hadassah: Five severe corona patients were treated with an innovative drug – and recovered


Hadassah Hospital announced that yesterday (Wednesday) the fifth of five corona patients, who were in critical condition, was released home after receiving innovative treatment in human cells taken from healthy donors, as part of the first clinical trial of its kind in the world.

The five patients – three of them in critical condition, and two in critical condition – were treated with Alostra, an innovative drug developed at Hadassah in collaboration with the biotechnology company Enlebex Therapeutics. The five were released from the hospital after treatment when they were healthy and negative for the virus, on average five to six days after receiving the drug.

The drug was developed on the basis of research by Prof. Dror Mevorach, director of the internal medicine department and the corona department at Hadassah. It has been successfully tried in the past on ten patients with sepsis (sepsis), which is considered a serious disease that currently has no cure. The trial in Corona patients was conducted under the approval of the Helsinki Committee of the Ministry of Health.

According to Prof. Mevorach, “Alostra is intended for the treatment of a wide range of cases where there is an overactivity of the immune system, which leads to an increase in the secretion of proteins by immune cells, called cytokines, and causes a cytokine storm. Its activity is carried out by treating cells taken from a healthy donor And Hindus in the laboratory, in such a way that when we inject them into the patient’s body, we control the inflammation or cytokine storm that is very harmful to the patients. “

Hadassah CEO Prof. Zeev Rothstein added: “Despite the war around, and alongside intensive preparations to absorb the growing numbers of critically ill patients, Hadassah continues to innovate and lead the breakthroughs in the care of these corona patients. We are happy that a drug developed in a study within the walls of our hospital does indeed show therapeutic potential in these patients. “

“We are pleased that the patients in a difficult and critical condition have recovered as a result of the treatment with Allstra.”

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