The trial came after an initial safety trial in which the potential vaccine was tested on subjects between the ages of 18 and 55. In the follow-up trial, the vaccine was administered to 40 adults in the age groups 56 to 70 and 71 and older.
Elderly people who received two doses of 100 micrograms 28 days apart showed an immune response similar to that of young adults. Moderna is already testing a higher dose in a phase 3 trial. This is the final stage before requesting approval.
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The subjects rated the side effects, including headache, fatigue, body aches, chills, and pain at the injection site, mild to moderate. In at least two cases, subjects showed serious side effects.
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