Significant results from the advanced corona vaccine trial of the American company Modern are expected only in November at the earliest, but in the meantime the company has released information from a small previous experiment. According to which the vaccine is safe for use in adults, and it produces antibodies in them in an amount similar to that observed in young people. It is not yet known whether these antibodies found in the volunteers’ blood will actually protect them from contracting the disease – this is actually what the company went out to test in a Phase 3 trial it is currently conducting in 30,000 people in the US. However, the fact that adults also develop antibodies That if the vaccine works at all, it will also work in this population, for which it is most important.It was not obvious, because the immune system weakens with age.
The side effects from the vaccine in the trial were similar to the side effects that high-dose flu vaccines produce – mild fever, headache, muscle aches, tremors, weakness and pain in the injection site. Subjects described the side effects as moderate. However there were two slightly more severe cases: one subject developed a high fever, and another subject developed fatigue that shut him down from activity that day. In both cases the symptoms passed the next day. Other infected people had no side effects at all.
These days the world is waiting for preliminary results from the clinical trials in vaccines of the American companies Pfizer (together with the German Biontech), which are expected as early as October; Modern, expected in November and Johnson & Johnson and Nova-Vox, expected by the end of the year. In all cases there is a good chance that at the relevant times the companies will report that there is still not enough information to determine whether the vaccine is effective, and that one has to wait until the end of the experiment.
Another company, AstraZeneca, is currently conducting an experiment in the United Kingdom, but its trial in the United States has meanwhile been frozen, after a serious side effect appeared in one subject that is still unclear if it was caused by the vaccine. .
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