Modern with an optimistic update: The vaccine is safe for use in adults

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The significant results from the advanced trial of the American modern company Corona vaccine are expected to arrive only in November at the earliest. In the meantime, however, the company has released information from another small experiment that showed that the vaccine is safe for use in adults, and produces antibodies in them in an amount similar to that observed in young people. It is not yet known whether these antibodies will actually protect volunteers from contracting the disease – this issue is currently being tested in a Phase 3 trial, which the company is conducting in 30,000 people in the US. It will also be effective for this population – for whom it is most important.It was not obvious because the immune system weakens with age.

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The side effects from the vaccine in the trial were similar to the side effects that high-dose flu vaccines produce – mild fever, headache, muscle aches, tremors, weakness and pain in the injection site. Subjects described the side effects as moderate. However there were two slightly more severe cases: one subject developed a high fever, and another subject developed fatigue that shut him down from activity that day. In both cases, the symptoms were reversed. Other infected people had no side effects at all.

Caring for the elderly during Corona | Photo: Nati Shochat, Flash 90

These days the world is waiting for preliminary results from the clinical trials in vaccines of the American companies Pfizer (together with the German Biontech), which are expected as early as October; Moderna, which is expected in November and Johnson & Johnson and Nova-Vox, which are expected until the end of the year. In all cases there is a good chance that at the relevant times the companies will report that there is still not enough information to determine whether the vaccine is effective, and that one has to wait until the end of the experiment.

Another company, AstraZeneca, is currently conducting an experiment in the United Kingdom, but its trial in the United States has meanwhile been frozen, after a serious side effect appeared in one subject that is still unclear if it was caused by the vaccine. .

The original article was published in Globes.







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